Docs / Encryption & encoding
Base64Encode is an AMPscript function in the encryption & encoding category. UTF-8.
Base64Encode(str, [charset])
%%=Base64Encode("Hello Ada")=%%
SGVsbG8gQWRh
Output produced by AmpSend's AMPscript engine (validated against Salesforce's own test corpus) - not a hand-written result.
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Base64Encode in the official AMPscript reference - or browse the official index of AMPscript functions for platform behavior and edge cases.